Just echoing what Trin said... spirit activity is usually linked to the history of a place. If a location is haunted, it usually means something happened there in the past, usually that someone died there, either violently, or they loved the place and don't want to leave.
If you're building a new house on a new lot that was formerly unoccupied, the chances are good that it won't be haunted. The only exceptions would be, like Trin said, if the land itself has activity, or if you or your belongings carry something along with them.
I wouldn't build a new house "just" to ensure that it's unhaunted. Only a small percentage of existing dwellings are haunted to begin with. Of course, if you have other reasons to build, go for it.
I'm in a similar situation where I'm building a new house. Our old house burned down in January, and we lost our 3 cats in the fire. So, in this case I'm hoping I'll get to experience the spirits of my former furbabies in the new house, which is being built in the same spot as the old house. We're hoping to move in next month if all goes well!